2. Natural Products
  3. Endogenous metabolite
  4. Disease markers
  5. Other disease

Other disease

Other disease (43):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0075
    Melatonin 73-31-4 99.93%
    Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress.
    Melatonin
  • HY-F0004
    β-Nicotinamide mononucleotide 1094-61-7 99.90%
    β-nicotinamide mononucleotide (β-NM) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of β-nicotinamide mononucleotide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity.
    β-Nicotinamide mononucleotide
  • HY-N0437
    Progesterone 57-83-0 99.79%
    Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone
  • HY-76847
    Chenodeoxycholic Acid 474-25-9 99.90%
    Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Chenodeoxycholic Acid
  • HY-13771
    Ursodeoxycholic acid 128-13-2 ≥98.0%
    Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active.
    Ursodeoxycholic acid
  • HY-113137R
    N2,N2-Dimethylguanosine (Standard) 2140-67-2
    N2,N2-Dimethylguanosine (Standard) is the analytical standard of N2,N2-Dimethylguanosine. This product is intended for research and analytical applications. N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.
    N2,N2-Dimethylguanosine (Standard)
  • HY-N0324
    Cholic acid 81-25-4 99.83%
    Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.
    Cholic acid
  • HY-32351
    Calcifediol 19356-17-3 99.94%
    Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels.
    Calcifediol
  • HY-W050026
    Phenylacetylglutamine 28047-15-6 99.02%
    Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation.
    Phenylacetylglutamine
  • HY-116084
    Trimethylamine N-oxide 1184-78-7 ≥98.0%
    Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway.
    Trimethylamine N-oxide
  • HY-101410
    SDMA 30344-00-4 ≥98.0%
    SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.
    SDMA
  • HY-W010382
    Oxaloacetic acid 328-42-7 99.88%
    Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function.
    Oxaloacetic acid
  • HY-113061
    Pseudouridine 1445-07-4 99.93%
    Pseudouridine is an isomer of the nucleoside uridine, and the most abundant modified nucleoside in non-coding RNAs. Pseudouridine in rRNA and tRNA can fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation.
    Pseudouridine
  • HY-N0016
    Glycitein 40957-83-3 99.67%
    Glycitein is a soy isoflavone used to study apoptosis and antioxidant.
    Glycitein
  • HY-113329
    Guanidinoethyl sulfonate 543-18-0 ≥98.0%
    Guanidinoethyl sulfonate (Taurocyamine), a transport antagonist of taurine, induces much urinary taurine excretion with a resulting decrease in the tissue taurine content and readily produces taurine-deficient fetal rats in pregnant rats. Guanidinoethyl sulfonate, a structural analogue of taurine, acts as a competitive inhibitor of taurine transport.
    Guanidinoethyl sulfonate
  • HY-Y0511
    N-Methylsarcosine 1118-68-9 ≥98.0%
    N-Methylsarcosine is an amino acid building block for protein, found in a small amount in the body.
    N-Methylsarcosine
  • HY-W011540
    8-Hydroxy-2'-deoxyguanosine 88847-89-6
    8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.
    8-Hydroxy-2'-deoxyguanosine
  • HY-W021448
    Glycocyamine 352-97-6 ≥98.0%
    Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.
    Glycocyamine
  • HY-113524
    N-Acetyl-L-aspartic acid 997-55-7 99.45%
    N-Acetyl-L-aspartic acid is a derivative of aspartic acid.
    N-Acetyl-L-aspartic acid
  • HY-113432
    Nudifloramide 701-44-0 99.94%
    Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro.
    Nudifloramide